London's Secret to Unlocking the Mystery of Young Adults' Colorectal Cancer Surge
In a bid to crack the code behind the alarming rise in colorectal cancer cases among young adults, researchers are scouring through century-old tumor samples stored in London's National Bowel Hospital. The unusual archive, which boasts tens of thousands of paraffin-preserved tissue samples and gut bacteria from every patient ever treated for colorectal cancer at the hospital, is being hailed as a treasure trove by scientists.
Contrary to overall trends, where colorectal cancer rates have been steadily declining, there has been a disturbing uptick in cases among individuals under 55. In fact, one in five people diagnosed with colorectal cancer now fall into this age category. The US-based American Cancer Society reports that men under 50 are increasingly succumbing to the disease as their leading cause of death, while women in the same bracket rank second.
Despite the growing concern, the underlying reasons behind these rising rates remain shrouded in mystery. Experts point to several potential contributing factors, including an increased reliance on ultra-processed food, sedentary lifestyles, and soaring obesity rates. However, a specific culprit has yet to be pinpointed.
A team of researchers at the Institute of Cancer Research in the UK is now examining these century-old tumor samples using molecular DNA analysis to uncover patterns of colorectal cancer among younger adults. The breakthroughs they hope to glean from this analysis could potentially shed light on why certain types of gut bacteria, such as E. coli, which were previously absent or present in different forms, have become increasingly prevalent.
The Institute's Trevor Graham believes that these "toxic" bacteria may be responsible for the growth of cancerous cells, sparking a heated debate within the scientific community. As researchers dig into this complex issue, one thing is certain β uncovering the truth behind colorectal cancer's mysterious resurgence will require perseverance and a deep dive into this rich, 100-year-old archive.
In a bid to crack the code behind the alarming rise in colorectal cancer cases among young adults, researchers are scouring through century-old tumor samples stored in London's National Bowel Hospital. The unusual archive, which boasts tens of thousands of paraffin-preserved tissue samples and gut bacteria from every patient ever treated for colorectal cancer at the hospital, is being hailed as a treasure trove by scientists.
Contrary to overall trends, where colorectal cancer rates have been steadily declining, there has been a disturbing uptick in cases among individuals under 55. In fact, one in five people diagnosed with colorectal cancer now fall into this age category. The US-based American Cancer Society reports that men under 50 are increasingly succumbing to the disease as their leading cause of death, while women in the same bracket rank second.
Despite the growing concern, the underlying reasons behind these rising rates remain shrouded in mystery. Experts point to several potential contributing factors, including an increased reliance on ultra-processed food, sedentary lifestyles, and soaring obesity rates. However, a specific culprit has yet to be pinpointed.
A team of researchers at the Institute of Cancer Research in the UK is now examining these century-old tumor samples using molecular DNA analysis to uncover patterns of colorectal cancer among younger adults. The breakthroughs they hope to glean from this analysis could potentially shed light on why certain types of gut bacteria, such as E. coli, which were previously absent or present in different forms, have become increasingly prevalent.
The Institute's Trevor Graham believes that these "toxic" bacteria may be responsible for the growth of cancerous cells, sparking a heated debate within the scientific community. As researchers dig into this complex issue, one thing is certain β uncovering the truth behind colorectal cancer's mysterious resurgence will require perseverance and a deep dive into this rich, 100-year-old archive.