Lithium levels in drinking water linked to autism diagnoses - but experts caution against jumping to conclusions.
A new study has found a modestly higher risk of autism spectrum disorder (ASD) in children born to pregnant women who consumed tap water with elevated lithium levels. However, the researchers emphasize that the association does not imply a direct causal link between lithium exposure and ASD diagnosis.
The findings are based on a large database of Danish cases, where researchers measured lithium concentrations in public waterworks serving more than half the population between 2000 and 2013. The study revealed a moderate increase in risk for children exposed to higher levels of lithium during pregnancy, with a 24% to 26% higher risk compared to those at lower exposure levels.
The Danish government's lack of regulation on drinking water lithium levels has enabled this investigation. Lithium is commonly used in medications and other industrial applications, as well as being an essential nutrient for human health.
However, more research is necessary before a definitive connection between lithium levels in tap water and ASD diagnoses can be established. Dr. Beate Ritz, co-author of the study, emphasized that any potential effects should be thoroughly explored through replication.
The implications of this discovery are complex when it comes to public health policy. While elevated lithium levels have been linked with increased psychiatric hospitalizations and lower rates of suicide, studies examining its impact on autism diagnoses remain inconclusive.
Other experts argue that establishing a causal relationship between ASD and environmental exposures is difficult due to the numerous confounding factors involved. "We need to separate the signal from the noise," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Childrenβs Hospital in Cleveland.
A new study has found a modestly higher risk of autism spectrum disorder (ASD) in children born to pregnant women who consumed tap water with elevated lithium levels. However, the researchers emphasize that the association does not imply a direct causal link between lithium exposure and ASD diagnosis.
The findings are based on a large database of Danish cases, where researchers measured lithium concentrations in public waterworks serving more than half the population between 2000 and 2013. The study revealed a moderate increase in risk for children exposed to higher levels of lithium during pregnancy, with a 24% to 26% higher risk compared to those at lower exposure levels.
The Danish government's lack of regulation on drinking water lithium levels has enabled this investigation. Lithium is commonly used in medications and other industrial applications, as well as being an essential nutrient for human health.
However, more research is necessary before a definitive connection between lithium levels in tap water and ASD diagnoses can be established. Dr. Beate Ritz, co-author of the study, emphasized that any potential effects should be thoroughly explored through replication.
The implications of this discovery are complex when it comes to public health policy. While elevated lithium levels have been linked with increased psychiatric hospitalizations and lower rates of suicide, studies examining its impact on autism diagnoses remain inconclusive.
Other experts argue that establishing a causal relationship between ASD and environmental exposures is difficult due to the numerous confounding factors involved. "We need to separate the signal from the noise," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Childrenβs Hospital in Cleveland.