Amlodipine Side Effects On Potassium Levels

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Amlodipine is a commonly prescribed medication for hypertension and angina. It works by relaxing the blood vessels, allowing blood to flow more easily. However, like any medication, amlodipine has potential side effects, including on potassium levels in the body.

What is Potassium?

Potassium is an essential mineral that plays a vital role in many bodily functions, including muscle and nerve activity, fluid balance, and heart health. Normal potassium levels range from 3.5 to 5.0 millimoles per liter (mmol/L) in the blood.

Amlodipine and Hypokalemia

Amlodipine can cause a decrease in potassium levels in some people, a condition called hypokalemia. This is because amlodipine can increase the amount of potassium that is excreted in the urine. Symptoms of hypokalemia include weakness, fatigue, muscle cramps, and irregular heartbeat.

Who is at Risk?

Not everyone who takes amlodipine will experience hypokalemia. However, certain factors can increase the risk, including taking other medications that also lower potassium levels, such as diuretics, or having kidney problems. Older adults may also be more susceptible to hypokalemia.

Preventing Hypokalemia

If you are taking amlodipine, your doctor may monitor your potassium levels with blood tests. They may also recommend increasing your intake of potassium-rich foods, such as bananas, oranges, spinach, and sweet potatoes. In some cases, they may also prescribe potassium supplements.

Other Side Effects of Amlodipine

In addition to hypokalemia, amlodipine can also cause other side effects, including headache, dizziness, flushing, and swelling in the ankles and feet. More serious side effects, although rare, can include liver problems, allergic reactions, and low blood pressure.


If you are taking amlodipine, it is important to be aware of the potential side effects, including on potassium levels. Talk to your doctor if you experience any symptoms of hypokalemia or other side effects. They may recommend adjusting your medication or prescribing additional treatments to manage your symptoms and maintain your overall health.


The information in this article is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition.