Scientists in Germany claim to have made a breakthrough in the development of a nasal vaccine that can effectively combat Covid-19 by targeting the upper respiratory tract. The experimental vaccine uses a live but weakened form of the virus and has shown promising results in hamster trials, achieving "sterilizing immunity" and preventing illness.
In the studies, two doses of the vaccine were found to block the virus from copying itself in the animals' upper airways, resulting in "sterilizing immunity". This is a long-sought goal for researchers working on Covid-19 vaccines. The nasal vaccine previews the entire coronavirus for the body, allowing the hamsters to create immune weapons against a wider range of targets.
While this development holds promise, vaccine experts caution that the vaccine still needs to pass more tests before it's ready for use. However, if successful, it could potentially provide an effective solution to Covid-19 by boosting mucosal immunity and preventing infection in the upper respiratory tract.
Several nasal vaccines are currently in various stages of clinical trials, with some already showing promising results. Other countries, such as China and India, have also approved nasal vaccines for use, but effectiveness data has yet to be published.
The development of a Covid-19 vaccine that targets mucosal immunity is crucial, as the virus continues to mutate and spread among people and animals. According to Dr. Greg Poland, a vaccine expert at the Mayo Clinic, "That's foolish. We should be developing a pan-coronavirus vaccine that does induce mucosal immunity and that is long-lived."
Several nasal vaccines are nearing completion of their trials, including one developed by Codagenix in Germany, which uses a live but weakened version of the virus. The results of these studies may come later this year.
While there have been challenges in developing effective inhaled vaccines for respiratory infections like Covid-19, some vaccines, such as those against flu and measles, have shown promising results using live attenuated viruses. However, it's essential to note that live vaccines can't be taken by everyone, particularly those with compromised immunity.
The potential development of a nasal vaccine targeting mucosal immunity has sparked hope among researchers and experts, who believe it could provide an effective solution to the ongoing Covid-19 pandemic.
In the studies, two doses of the vaccine were found to block the virus from copying itself in the animals' upper airways, resulting in "sterilizing immunity". This is a long-sought goal for researchers working on Covid-19 vaccines. The nasal vaccine previews the entire coronavirus for the body, allowing the hamsters to create immune weapons against a wider range of targets.
While this development holds promise, vaccine experts caution that the vaccine still needs to pass more tests before it's ready for use. However, if successful, it could potentially provide an effective solution to Covid-19 by boosting mucosal immunity and preventing infection in the upper respiratory tract.
Several nasal vaccines are currently in various stages of clinical trials, with some already showing promising results. Other countries, such as China and India, have also approved nasal vaccines for use, but effectiveness data has yet to be published.
The development of a Covid-19 vaccine that targets mucosal immunity is crucial, as the virus continues to mutate and spread among people and animals. According to Dr. Greg Poland, a vaccine expert at the Mayo Clinic, "That's foolish. We should be developing a pan-coronavirus vaccine that does induce mucosal immunity and that is long-lived."
Several nasal vaccines are nearing completion of their trials, including one developed by Codagenix in Germany, which uses a live but weakened version of the virus. The results of these studies may come later this year.
While there have been challenges in developing effective inhaled vaccines for respiratory infections like Covid-19, some vaccines, such as those against flu and measles, have shown promising results using live attenuated viruses. However, it's essential to note that live vaccines can't be taken by everyone, particularly those with compromised immunity.
The potential development of a nasal vaccine targeting mucosal immunity has sparked hope among researchers and experts, who believe it could provide an effective solution to the ongoing Covid-19 pandemic.
️ Just like life is full of uncertainties, let's take a step forward in the right direction 
, we gotta keep pushing for a world where everyone has access to a vaccine that works 
! But seriously, it's crazy how far scientists have come with this nasal vaccine and I'm hyped to see what the future holds 
.
Scientists in Germany think they've found a way to make a vaccine that might actually work for once, but we're still gonna die from Covid-19 
. They've got some promising results with a nasal vaccine that can stop the virus from copying itself in our noses, but it's not out yet and we gotta wait till more tests are done 
. Even if it does make it to market, it might only work for some people or be taken by those who have compromised immune systems, which is just great 
. The virus keeps mutating so we'll probably still be stuck in this never-ending cycle of Covid-19 
. And on the bright side, there's another nasal vaccine coming out soon that might do something similar, but let's not get our hopes up too high 
.
I'm thinking, if they can get this one right, it'll be a game changer for people with compromised immunity or those who don't respond well to traditional vaccines 
. And it's not just about Covid-19, but also flu and other respiratory infections... what about all the other viruses out there? Do we really need a pan-coronavirus vaccine that lasts forever? 
It sounds like Dr. Poland is saying we should aim high, but also be realistic about the challenges of developing a vaccine that works for everyone 
. Can we get to that point without causing more harm than good? 
I'd love to see more details on the hamster trials and how they relate to human trials... are the results really that promising? 
. The fact that it can target a wider range of targets because it previews the entire coronavirus for the body is just genius. And let's be real, mucosal immunity is key to stopping this pandemic from spreading. I'm not surprised that experts are saying we should be developing a pan-coronavirus vaccine that does induce mucosal immunity and is long-lived... sounds like common sense to me 
. The challenges of inhaled vaccines haven't been an issue for flu or measles, so why can't we figure this out? Fingers crossed these trials go smoothly and this vaccine becomes a reality soon 
If it works out, it could be a game-changer for Covid-19 
prevention. I mean, we've been stuck with these vaccines that don't really work on the upper respiratory tract, so anything that can boost mucosal immunity would be awesome 
. But, gotta remember, it's still in trial stages and all that jazz 
. Fingers crossed it'll make it out alive 
! And did you know that there are already 4 nasal vaccines in clinical trials? 
This is a great sign, though! And have you seen those charts showing how effective vaccines are in reducing hospitalizations? It's like 90% reduction, dude 
!
. Maybe they'll expand to human trials soon and we'll see real-life results.
i've been hearing about covid for ages in school health class and we just learned about how it affects our noses & lungs lol but seriously though if a nasal vaccine can really stop the virus from copying itself in our upper airways that would be insane 
! I mean, think about it - no more sniffles and sneezes just because you got a little too close to someone with Covid 
. This could be a total game-changer for people who are already sick or have compromised immune systems. And the fact that it's targeting mucosal immunity is like, so cool 
! I've been seeing some rough layouts on websites and blogs lately, but if this vaccine works out, we'll be able to get back to using design principles in a whole new way 
. I'm talking clean lines, plenty of white space, and just a general sense of calm and professionalism. This is gonna be a great year for design, mark my words 
!
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. The fact that it's using a live but weakened form of the virus and has shown promising results in hamster trials is super encouraging 
. I'm not surprised that experts are cautioning more tests need to be done, but fingers crossed they get it right next time 
. But seriously, this breakthrough on a nasal vaccine for Covid sounds super promising! I've been seeing these new mRNA vaccines popping up everywhere and they seem to be doing the trick. It's crazy how scientists are racing against time to develop an effective solution for this pandemic. If it works out, that would be a huge win for humanity 
just heard about this new nasal vaccine in germany 
that's supposed to be super effective against covid-19 
read more here 
lol i no vaccine experts r like "okay let's slow down" but idc they'll prob figure it out 
It's like, finally, we're getting close to something that can actually keep us safe from all these mutations 
. I mean, think about it, a live but weakened virus? That sounds crazy genius 
. This one has all the potential to be a game-changer 
. Can't wait to see what happens later this year 
. I'm not saying it can't work, but I'd rather stick with tried-and-true methods over some experimental gamble 
. I mean, achieving that kind of immunity would be huge 
. More tests need to happen before this vaccine is ready for prime time 
.
. That's where things get really interesting 
. We need to think bigger and create a pan-coronavirus vaccine that can cover all bases 
. That's the only way we'll ever get ahead of this mutating virus