Fossilized feces from Mexico's ancient 'Cave of the Dead Children' have provided a unique glimpse into the intestinal parasites and diet of people living over 1,000 years ago. The findings suggest that intestinal infections such as pinworm and Shigella were common among the Loma San Gabriel people who inhabited the cave around 1,200 to 1,400 years ago.
The study used a new technique called qPCR to analyze DNA from 10 of these ancient fecal samples, which is more targeted than traditional DNA sequencing. The analysis revealed the genetic signatures of various gut parasites, including Blastocystis and multiple strains of E. coli, as well as pinworms in the majority of samples.
The discovery was surprising given that the DNA from these pathogens had been expected to degrade over time, and it highlights the potential for modern molecular methods to inform studies of the past. The study's authors believe that this technique could be used to analyze other ancient fecal samples, potentially revealing new insights into the health and living conditions of our ancestors.
The Cave of the Dead Children, also known as La Cueva de Los Muertos Chiquitos, is a site in northern Mexico where archaeologists have uncovered over 500 ancient desiccated fecal samples and more than a dozen skeletons of children who died under mysterious circumstances. The cave's dry climate has helped preserve these ancient samples for thousands of years.
The study's findings offer a fascinating glimpse into the lives of people living in the past, highlighting the challenges they faced with regards to health and sanitation. While the study was limited to 10 samples, it provides a proof-of-concept for using qPCR to identify intestinal parasites in ancient feces, which could be applied to larger studies in the future.
The study used a new technique called qPCR to analyze DNA from 10 of these ancient fecal samples, which is more targeted than traditional DNA sequencing. The analysis revealed the genetic signatures of various gut parasites, including Blastocystis and multiple strains of E. coli, as well as pinworms in the majority of samples.
The discovery was surprising given that the DNA from these pathogens had been expected to degrade over time, and it highlights the potential for modern molecular methods to inform studies of the past. The study's authors believe that this technique could be used to analyze other ancient fecal samples, potentially revealing new insights into the health and living conditions of our ancestors.
The Cave of the Dead Children, also known as La Cueva de Los Muertos Chiquitos, is a site in northern Mexico where archaeologists have uncovered over 500 ancient desiccated fecal samples and more than a dozen skeletons of children who died under mysterious circumstances. The cave's dry climate has helped preserve these ancient samples for thousands of years.
The study's findings offer a fascinating glimpse into the lives of people living in the past, highlighting the challenges they faced with regards to health and sanitation. While the study was limited to 10 samples, it provides a proof-of-concept for using qPCR to identify intestinal parasites in ancient feces, which could be applied to larger studies in the future.