Prescription for Weight Loss on the Rise Among Postpartum Women, Despite Safety Concerns
A new Danish study has found a significant increase in prescriptions for GLP-1 weight loss medications among postpartum women since the medications came to market. The study, published in JAMA Network, reveals that between 2018 and 2024, prescriptions for these medications rose from fewer than five per 10,000 women to nearly 173 per 10,000 - a staggering 2% of all new mothers.
While GLP-1 medications have been used to treat type 2 diabetes and obesity in the general population, their use among postpartum women is a relatively new development. Researchers are concerned about the potential impact on breastfeeding, as little data exists on how these medications interact with natural hormonal changes that occur during this period.
According to Dr. Jonathan Zipursky, a clinical pharmacologist at the University of Toronto, "We simply do not know how weight-loss medication interacts with those processes or whether it could affect normal physiological recovery." Additionally, there is limited research on whether these drugs can transfer to breastmilk and whether exposure to them is safe for nursing babies.
While some studies suggest that GLP-1 medications may not enter breast milk at high levels of concentration and break down in babies' stomachs, experts advise caution. Dr. Zipursky recommends that breastfeeding women refrain from taking weight loss medications after giving birth "out of an abundance of caution." The lack of data on the subject means that women who breastfeed should be aware of the potential risks and consider alternative treatment options.
The increased use of GLP-1 medications among postpartum women highlights the need for more research into their safety and efficacy during this critical period. As Dr. Mette Bliddal, one of the researchers behind the study, notes, "In just a few years, GLP-1 medications have become a real part of postpartum care for many women... but we are still in the dark about how they interact with natural physiological changes during this time."
A new Danish study has found a significant increase in prescriptions for GLP-1 weight loss medications among postpartum women since the medications came to market. The study, published in JAMA Network, reveals that between 2018 and 2024, prescriptions for these medications rose from fewer than five per 10,000 women to nearly 173 per 10,000 - a staggering 2% of all new mothers.
While GLP-1 medications have been used to treat type 2 diabetes and obesity in the general population, their use among postpartum women is a relatively new development. Researchers are concerned about the potential impact on breastfeeding, as little data exists on how these medications interact with natural hormonal changes that occur during this period.
According to Dr. Jonathan Zipursky, a clinical pharmacologist at the University of Toronto, "We simply do not know how weight-loss medication interacts with those processes or whether it could affect normal physiological recovery." Additionally, there is limited research on whether these drugs can transfer to breastmilk and whether exposure to them is safe for nursing babies.
While some studies suggest that GLP-1 medications may not enter breast milk at high levels of concentration and break down in babies' stomachs, experts advise caution. Dr. Zipursky recommends that breastfeeding women refrain from taking weight loss medications after giving birth "out of an abundance of caution." The lack of data on the subject means that women who breastfeed should be aware of the potential risks and consider alternative treatment options.
The increased use of GLP-1 medications among postpartum women highlights the need for more research into their safety and efficacy during this critical period. As Dr. Mette Bliddal, one of the researchers behind the study, notes, "In just a few years, GLP-1 medications have become a real part of postpartum care for many women... but we are still in the dark about how they interact with natural physiological changes during this time."