Study Reveals Most Statin Side-Effects Unrelated to Medication
A groundbreaking review of evidence has found that nearly all side effects listed on statin labels are not caused by the medication itself. The study, published in the Lancet, examined 19 randomized controlled trials involving over 124,000 people and found no strong evidence to support statins causing 62 out of 66 commonly listed side effects.
According to researchers, these side effects include memory problems, depression, sleep disturbances, and nerve damage. However, the study revealed that the risk of most of these side effects was extremely low, with some effects being virtually non-existent.
For instance, the percentage of people suffering from memory loss or sleep problems per year was found to be similar among those taking statin therapy as well as those not taking the medication. This suggests that statins do not contribute to these commonly experienced events.
The study's findings have significant implications for patients and doctors who have been concerned about the safety of statins due to long-running safety concerns. According to the lead author, Christina Reith, "we now have really good evidence that although these things may well happen to people while they take statins, that statins are not the cause of these problems."
In light of this new evidence, experts are urging for rapid revision of statin labels to better reflect the findings. Prof Sir Rory Collins stated that "statin information requires rapid revision" and that this will help patients and doctors make more informed decisions.
The British Heart Foundation, which part-funded the research, described the study as a "much-needed counter to misinformation around statins". The organization's chief scientific and medical officer added that statins are life-saving drugs that have been proven to protect against heart attacks and strokes, and this evidence should help prevent unnecessary deaths from cardiovascular disease.
A groundbreaking review of evidence has found that nearly all side effects listed on statin labels are not caused by the medication itself. The study, published in the Lancet, examined 19 randomized controlled trials involving over 124,000 people and found no strong evidence to support statins causing 62 out of 66 commonly listed side effects.
According to researchers, these side effects include memory problems, depression, sleep disturbances, and nerve damage. However, the study revealed that the risk of most of these side effects was extremely low, with some effects being virtually non-existent.
For instance, the percentage of people suffering from memory loss or sleep problems per year was found to be similar among those taking statin therapy as well as those not taking the medication. This suggests that statins do not contribute to these commonly experienced events.
The study's findings have significant implications for patients and doctors who have been concerned about the safety of statins due to long-running safety concerns. According to the lead author, Christina Reith, "we now have really good evidence that although these things may well happen to people while they take statins, that statins are not the cause of these problems."
In light of this new evidence, experts are urging for rapid revision of statin labels to better reflect the findings. Prof Sir Rory Collins stated that "statin information requires rapid revision" and that this will help patients and doctors make more informed decisions.
The British Heart Foundation, which part-funded the research, described the study as a "much-needed counter to misinformation around statins". The organization's chief scientific and medical officer added that statins are life-saving drugs that have been proven to protect against heart attacks and strokes, and this evidence should help prevent unnecessary deaths from cardiovascular disease.