I'm not sure I buy this... I mean, HMGN1 is involved in causing heart defects in people with trisomy 21? That's a pretty big claim. Where are the study's results actually shown? Are they based on just animal models or did they do some actual human trials? And what's the sample size looking like here? I also don't get why this is such a huge deal. Trisomy 21 is a genetic disorder that's affected by only about 1 in 250 people worldwide... it's not like it's going to take over or anything. I'm all for finding new treatments, but let's not get ahead of ourselves here.
And what's with the implication that this is some kind of 'breakthrough' discovery? Have we been missing out on a cure for trisomy 21-related heart defects all these years because HMGN1 was just sitting there waiting to be discovered?
