Study Finds Slightly Higher Risk of Autism Diagnosis Linked to High Lithium Levels in Tap Water, But More Research Needed.
A new study published in the journal JAMA Pediatrics has found a modest association between exposure to high levels of lithium in tap water and an increased risk of autism spectrum disorder (ASD) in children. The research, which was conducted in Denmark where lithium levels in drinking water are similar to those in US systems, suggests that pregnant women who drank water with higher levels of lithium had a 24-46% higher risk of their child being diagnosed with ASD.
The study, which analyzed data from over 8,800 children born between 2000 and 2013, found that the association was most pronounced among those exposed to the highest levels of lithium. However, experts caution that this does not show a direct link between lithium exposure and autism diagnosis.
"We still don't know what causes autism, and genetics is likely playing a role," said Dr. Beate Ritz, a co-author of the study and professor of neurology at UCLA. "But it's clear that environmental factors can also play a part, and this research highlights the need for more studies on the topic."
The findings have implications for public health policy, as lithium levels in water are not regulated by the US Geological Survey. Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School, noted that "if these associations are valid, we'll need to develop guidelines for lithium in drinking water that protect the entire population."
However, other experts are more cautious, citing the need for further research before drawing conclusions about the relationship between lithium exposure and autism. Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, said "it's an interesting association, but causation is not proven."
The study's findings add to a growing body of evidence suggesting connections between environmental exposures and ASD. Research has also linked autism to exposure to pesticides, air pollution, and phthalates, but these factors have not been shown to be direct causes of the disorder.
In order to fully understand the relationship between lithium exposure and autism, more research is needed. As Dr. Wiznitzer noted, "we're bombarded with environmental stressors in our everyday lives. We need to figure out how to safely navigate them." The study's authors agree, stating that further replication of their findings in other countries will be necessary to establish a causal link between lithium exposure and autism.
A new study published in the journal JAMA Pediatrics has found a modest association between exposure to high levels of lithium in tap water and an increased risk of autism spectrum disorder (ASD) in children. The research, which was conducted in Denmark where lithium levels in drinking water are similar to those in US systems, suggests that pregnant women who drank water with higher levels of lithium had a 24-46% higher risk of their child being diagnosed with ASD.
The study, which analyzed data from over 8,800 children born between 2000 and 2013, found that the association was most pronounced among those exposed to the highest levels of lithium. However, experts caution that this does not show a direct link between lithium exposure and autism diagnosis.
"We still don't know what causes autism, and genetics is likely playing a role," said Dr. Beate Ritz, a co-author of the study and professor of neurology at UCLA. "But it's clear that environmental factors can also play a part, and this research highlights the need for more studies on the topic."
The findings have implications for public health policy, as lithium levels in water are not regulated by the US Geological Survey. Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School, noted that "if these associations are valid, we'll need to develop guidelines for lithium in drinking water that protect the entire population."
However, other experts are more cautious, citing the need for further research before drawing conclusions about the relationship between lithium exposure and autism. Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, said "it's an interesting association, but causation is not proven."
The study's findings add to a growing body of evidence suggesting connections between environmental exposures and ASD. Research has also linked autism to exposure to pesticides, air pollution, and phthalates, but these factors have not been shown to be direct causes of the disorder.
In order to fully understand the relationship between lithium exposure and autism, more research is needed. As Dr. Wiznitzer noted, "we're bombarded with environmental stressors in our everyday lives. We need to figure out how to safely navigate them." The study's authors agree, stating that further replication of their findings in other countries will be necessary to establish a causal link between lithium exposure and autism.