Can Lisinopril Cause Elevated Potassium?

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Lisinopril is a medication used to treat high blood pressure, heart failure, and to improve survival after a heart attack. It works by relaxing blood vessels, which helps to lower blood pressure. However, some people have reported elevated levels of potassium in their blood while taking lisinopril. In this article, we will explore whether lisinopril can cause elevated potassium levels and what you can do to prevent it.

What is Potassium?

Potassium is an essential mineral that plays a vital role in the proper functioning of the body. It helps to regulate the heartbeat, muscle contractions, and nerve impulses. However, when the level of potassium in the blood becomes too high, it can cause serious health problems such as irregular heartbeat, muscle weakness, and even paralysis.

How Does Lisinopril Affect Potassium Levels?

Lisinopril can cause elevated levels of potassium in the blood, a condition known as hyperkalemia. This is because lisinopril can decrease the amount of aldosterone produced by the adrenal glands. Aldosterone is a hormone that helps to regulate potassium levels in the body. When there is not enough aldosterone, potassium can build up in the blood.

Who is at Risk?

Not everyone who takes lisinopril will experience elevated potassium levels. However, certain people may be more at risk than others. These include: – People with kidney disease – People with diabetes – People who take other medications that can raise potassium levels, such as potassium supplements or certain diuretics

Symptoms of Elevated Potassium

In some cases, elevated potassium levels may not cause any symptoms. However, in others, it can cause: – Nausea – Fatigue – Weakness – Irregular heartbeat – Muscle weakness or paralysis

Preventing Elevated Potassium

If you are taking lisinopril, there are several things you can do to prevent elevated potassium levels. These include: – Avoiding potassium supplements or salt substitutes containing potassium – Eating a low-potassium diet – Monitoring your potassium levels regularly – Talking to your doctor about any other medications you are taking that can raise potassium levels


While lisinopril can cause elevated potassium levels in some people, it is not a common side effect. However, if you are taking lisinopril, it is important to be aware of the risk and take steps to prevent it. Talk to your doctor if you have any concerns or experience any symptoms of elevated potassium levels. With the right precautions, you can safely and effectively manage your high blood pressure with lisinopril.