The Function Of Albumin In Plasma: A Comprehensive Overview

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Albumin is a protein found in the plasma of our blood that plays a crucial role in maintaining the body’s fluid balance. It is produced in the liver and accounts for over 50% of the total protein in human plasma. This article provides a comprehensive overview of the function of albumin in plasma.

Transportation of Molecules

One of the primary functions of albumin is to transport various molecules, including hormones, fatty acids, and drugs, throughout the body. It binds to these molecules and carries them to their respective destinations. This function is essential for the proper functioning of various organs and systems in the body.

Maintenance of Osmotic Pressure

Albumin also plays a critical role in maintaining the osmotic pressure of our blood. Osmotic pressure refers to the pressure exerted by the solutes in a solution. In the case of our blood, albumin helps to balance the concentration of solutes inside and outside the blood vessels, thereby preventing excessive fluid from leaking into the surrounding tissues.

Regulation of pH Levels

Another crucial function of albumin is to regulate the pH levels of our blood. It acts as a buffer and helps to maintain the blood’s pH within a narrow range of 7.35 to 7.45. This is essential for the proper functioning of enzymes and other biochemical reactions in the body.

Immune System Function

Albumin also plays a role in the immune system function by binding to and transporting various substances, including antibodies and antigens. This helps to protect the body against infections and other foreign invaders.

Contribution to Wound Healing

Albumin is also essential for wound healing. It helps to maintain the integrity of the blood vessels, which is critical for the delivery of nutrients and oxygen to the injured tissue. Additionally, albumin also helps to reduce inflammation and promote tissue repair.

Role in Liver and Kidney Function

Albumin plays a crucial role in the functioning of both the liver and kidneys. In the liver, it helps to transport various substances, including bilirubin, which is a waste product of red blood cells. In the kidneys, albumin helps to maintain the proper balance of fluids and electrolytes in the body.

Impact of Albumin Deficiency

A deficiency in albumin can have severe consequences on the body. It can lead to edema, or swelling, in various parts of the body, including the legs, feet, and abdomen. It can also impact liver and kidney function, and increase the risk of infections and other health problems.


In conclusion, albumin is a critical protein found in the plasma of our blood that plays a variety of essential functions in the body. It helps to transport various molecules throughout the body, maintain the osmotic pressure and pH levels of our blood, and contribute to immune system function, wound healing, and liver and kidney function. A deficiency in albumin can have severe consequences on the body, highlighting the importance of this protein for our overall health and wellbeing.